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Sensodyne Raid Relief Toothpaste with fluoride is clinically proven to relieve the pain of sensitive teeth. Rapid Relief creates a physical seal against sensitivity triggers and when used twice a day, it provides long lasting protection from sensitivity. Sensodyne Rapid Relief acts rapidly to create a mineral-like seal over the surface of the dentine and within the microscopic channels. This prevents stimulus from reaching the nerve. Twice daily brushing provides long lasting protection from sensitivity. Also cleans, freshens and helps strengthen enamel.